This enzyme (CYP3A4) helps break down many commonly prescribed medications within the digestive tract. “all forms of the fruit (freshly squeezed juice, frozen concentrate and whole fruit) have the potential to reduce the activity of CYP3A4” ( CMAJ, March 5, 2013). David Bailey and his colleagues note that Now, some tell patients not to eat grapefruit at all when they are taking certain prescription drugs. When he first wrote about grapefruit juice interacting with medications, many health professionals were skeptical. So does the world’s leading expert on this interaction. There is ongoing confusion about the grapefruit-drug interaction issue. What Is the Story on Grapefruit Juice Drug Interactions?Ī. My mother lived to be 94, eating her daily grapefruit. He said that pressing the grapefruit for juice releases some chemical from the skin that is the culprit in the drug interaction. My pharmacist told me that it was OK for my mother to eat grapefruit with her blood pressure meds but that she must NOT drink grapefruit juice. Will Grapefruit Interact with Blood Pressure Pills? Pharmacists may dispense wildly different advice regarding potential reactions with specific medications. ![]() ![]() ![]() What do you know about the story on grapefruit juice and drug interactions? Some people have heard that it is risky to combine juice but not fruit with certain medications others insist that the interaction holds for the fruit as well as the juice.
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